Professor Jack Masquelier, a renowned French phyto-scientist, was the first to identify and isolate OPCs from French pine trees. Subsequently, he was awarded the first patent for his method for producing unique extract from the bark of French pine trees. Based on his research, Professor Masquelier also developed his breakthrough product – Masquelier’s® French Pine Bark Extract. As a powerful antioxidant, anti-inflammatory and antihistamine, research has shown that Pycnogenol can be used to support cardiovascular, respiratory and women’s health. It has applications for joint, eye and skin care, and can optimize cognitive and athletic performance. A study of 47 women with painful menstrual cramps who were given 30 mg Pycnogenol twice a day, showed subjects had fewer days of menstrual pain when taking the product.

• To date, more than 10 clinical trials have shown how Centellicum® can help improve several health conditions.
• People who have tried the capsules make it feasible to work more hours and enjoy their sleep even more than before.
• The antioxidant content of the extracts derived from Pine Bark and Grape Fruit contains liberal amounts of antioxidants that also acts as an antimugenic agent hence, could prevent DNA mutation.
• The NOW mission is – To provide value in products and services that empower people to lead healthier lives.
• Centuries later, a researcher by the name of Jacques Masquelier discovered that this recipe was so effective because of the pine barks ability to act as an antioxidant.
• Improve neuron’s resilience– Tannins, aka, proanthocyanidins, are times stronger than antioxidants such as vitamin C and E.
• Also do you know that shikimic acid, removed from the other bioflavonoids in pine is safe to use?
• An adequate dose of chloroquine appears to undermine this process, and in turn, viral replication in general, the authors noted.
• NHS has the exclusive rights to market and sell Pycnogenol in North America and benefits from more than 35 years of scientific research assuring the safety and efficacy of Pycnogenol as a dietary supplement.
• Market is changing rapidly with the ongoing expansion of the industry.
• Heart disease is the number one cause of premature death across the world, and it is caused by a number of factors.
• Many people make this mistake, which we believe to be a product of our “treat the symptoms, don’t prevent the disease” attitude to medicine and health.
• Similarly, pine bark extract does not seem to have much of an effect on testosterone, if any at all.
• Pinus pinaster is a type of pine tree native to areas of the Mediterranean including Portugal, Spain, France, and Morocco.

Pines are long lived and typically reach ages of 100–1,000 years, some even more. The longest-lived is the Great Basin bristlecone pine, Pinus longaeva. One individual of this species, dubbed “Methuselah”, is one of the world’s oldest living organisms at around 4,600 years old. It was discovered in a grove beneath Wheeler Peak and it is now known as “Prometheus” after the Greek immortal. Pine trees are evergreen, coniferous resinous trees growing 3–80 m (10–260 ft) tall, with the majority of species reaching 15–45 m (50–150 ft) tall.

French Maritime Pine Extract

If you are pregnant or breastfeeding, do not take pygeum supplements. There is not sufficient evidence to determine its safety during pregnancy. According to WebMD, doses of mg of pygeum extract have been used to treat BPH.

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The extraction process is such that saturated sodium chloride is added, and the bark is boiled. The process is repeated numerous times for the removal of condensed tannings. Comparing both extracts in terms of efficacy is so difficult to determine because Pine Bark Extract and Grape Seed Extract has similar components that are all beneficial to one’s health. The compounds that both extracts have are very useful to one’s health therefore comparing the two would be rootless considering all the health benefits that both extracts could offer.

Other side effects reported were dizziness, headache, and nausea also reported as mild. Safety studies have shown Pycnogenol safe with no mutagenic or teratogenic effects, no perinatal toxicity, and no negative fertility effects. Pycnogenol should not be taken during the first three months of pregnancy because there is no published data on pregnant women using Pycnogenol in the first trimester. I have found 3 academic articles in favour of pycnogenol to treat tinnitus.

Protects The Brain

Group 4 got the same treatment as group 2, but also received 20 mg/kg of pycnogenol. Group 1 received a daily injection of buffered saline and corn oil. Sooner or later, men who are into strength and/or muscle start to think about tinkering with their natural testosterone levels. However, hormonal manipulation generally brings with it the deep-seated fear that it’s going to cause our prostates to swell to Hindenburg-ish proportions. The group receiving the placebo did not register any detectable benefits. It has been found that immunosuppressants may interact with Pine Bark Extract.

In both groups that received extracts, there was a significant reduction in oxidative stress. No side effects or tolerability problems were observed with the plant extracts. By contrast, among subjects who received the additional pine bark extract without Centella, only 18.5% experienced atherosclerosis progression. One was treated with extract of pine bark alone, another was treated with pine bark and Centella asiatica, and a third control group received no extracts.

The control group did not experience any significant change in the said risk factors. Regarding its other antioxidant effects, the pine bark extract helps regenerate and protect vitamin C and E. Studies have proven multiple times that this extract exhibits anti-inflammatory activities. Modern science has now endorsed the traditional knowledge that maritime pine bark is rich in vitamin C. It further discovered that the phytochemicals in the bark, proanthocyanidins, are powerful antioxidants—even more potent than Vitamin C and E.

Improves Kidney Function

According to the website, you will feel the change even after a few days of receiving Bacopa extract, while your mood, focus, and cognitive functions will improve. Furthermore, Bacopa Monnieri is also a serotonin and GABA neurotransmitter producer. For that reason, it can quickly restore mental health, memory, and focus clarity to all people needing it. FDA has recently approved PS nootropic actions in people having cognitive disorders and loss of memory. Besides that, there is also evidence that PS can be a mood stabilizer and give better mental clarity to people who take it regularly.

A. A review of herbal preparations reports that Mediterranean pine bark extract eases “vasomotor symptoms,” doctor-speak for hot flashes (Maturitas, Feb. 2014). A randomized double-blind placebo-controlled trial found that Pycnogenol significantly improved such menopausal symptoms (Journal of Reproductive Medicine, Jan-Feb., 2013). For example, 100 mg of the supplement helped a group of asthmatic patients reduce their medication over a 6-month period , and over a 8-week period improved blood flow in patients with high blood pressure . The best way to reap the benefits of this potent extract is by taking an herbal supplement. There is a large assortment of products that contain this abundant herb. The most effective means of receiving pure, Pine Bark Extract is through products like pills capsules, powder, tea, essential oil, liquid and other support formulas.

And he or she looks for changes to the optic nerve such as thinning of the optic nerve or “cupping”. Those that have minimal changes in any of the above may be identified as “glaucoma suspects,” and typically requested to return for eye exams every 6 months. The oldest known Pine is located in the White Mountains of California CBD Gummies and is thought to be 4,600 years old and is called “Methuselah.” Pine Bark is thick and scaly bark of the Pine tree. The 5% pycnogenol group did heal faster than all others, but there was a less of an increase over the 2% group. Furthermore, the pycnogenol groups were left with smaller scars following healing.

Vitamin E Supplement

Additionally, women in the Pycnogenol® group reported significantly higher satisfaction with the treatment and near perfect (96%) compliance; the control group registered less than 50 percent compliance with treatment. Joyce Hollman is a writer based in Kennebunk, Maine, specializing in the medical/healthcare and natural/alternative health space. Health challenges of her own led Joyce on a journey to discover ways to feel better through organic living, utilizing natural health strategies. Now, practicing yoga and meditation, and working towards living in a chemical-free home, her experiences make her the perfect conduit to help others live and feel better naturally. Pine bark extract can be found in liquid, tablet or capsule form.

Pine Bark Extract Pinus Pinaster

There is insufficient evidence to support the use of Pycnogenol for any of the uses listed below. It should never be used as a replacement for approved medical therapies. A trial of 53 students found that pycnogenol may improve cognitive function, memory, attention, mood, and mental performance after 8 weeks . Pycnogenol (100 mg/day) may reduce hay fever symptoms, according to a clinical trial of 39 people. Another clinical trial of 76 people with allergic asthma also suggests that Pycnogenol may reduce IgE antibodies and asthma symptoms .

However, healthy people are not immune and can also develop mild infections, in particular after being in improperly chlorinated hot tubs or swimming pools. We all know the power of antioxidants to improve health and the high-antioxidant foods we should eat regularly. Still, rigorous research on the effectiveness of pine bark extract in humans is lacking, and more randomized controlled-trial studies are needed. So, it’s too soon to say how safe and effective pine bark extracts are for treating specific illnesses .

The smallest are Siberian dwarf pine and Potosi pinyon, and the tallest is an 81.79 m (268.35 ft) tall ponderosa pine located in southern Oregon’s Rogue River-Siskiyou National Forest. While there is no distinct “feeling” associated with pycnogenol , it still makes sense to start at a smaller dose range and then move up to 100 – 200 mg once it seems safe to do so. Pycnogenol does interact with inflammatory markers and other blood markers, which are usually positive, but could be a side effect that one doesn’t expect. But the actual bioavailability of this complex mixture is still unknown. Since components of Pycnogenol can be modified during digestion and absorption as well as by the liver, diseases that affect the gut or liver may increase or decrease its effects .

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Results from a 2012 study in the journal Pediatrics suggest that all children should be checked for adequate vitamin D levels. This is especially important for those with dark skin, since they don’t get vitamin D as easily from exposure to sunlight. Antiviral results suggest that How do Delta 8 Disposables vape work? Pycnogenol exerts its beneficial effects on viral myocarditis (an inflammation of the heart muscle – myocardium). Human herpesvirus 6 (HHV-6) symptoms are very much like the Coronavirus (CoVid-19). Pine Bark a natural product, possesses antidiabetic and antiviral properties.

Purchasing Pycnogenol

After four weeks, STS scores reduced to 5.2 in the low dose group and 3.3 in the high dose group, demonstrating a dramatic reduction of the disturbing background noise in the effected ear. The process of manufacturing powdered extracts is straight forward, but requires highly advanced and specialized equipment. A high level of quality assurance is also needed, from analyzing each batch of herbs for contamination and heavy metals and also testing to ensure the correct plant species and variety is being used. After quality assurance is done, the bulk herbs are combined with water, similar to making a water soluton of herbs at home. This water extract is then reduced in large vats over low heat until the desired concentration is obtained. For some powdered extracts, a standardized extract is performed, where a certain levels of an active compound of the plant is targeted.

Study Finds Pycnogenol® May Reduce Frequency Of Migraines And Severity Of Symptoms

This super-nutrient is being used to get much more energy, build a stronger immune system, get rid of aches and pains, have a clearer, and sharper brain, better circulation, healthier blood pressure, and better sleep. Around 1951, a French researcher named Jacques Masquelier came upon Cartier’s accounts of using regional tree bark extracts for his crew. Inspired, a quest began to find the active components in these various tree barks that imparted healing properties. Masquelier found that the most powerful active phytochemical ingredients were from the tree bark of a European coastal pine, Pinus pinaster. In the group without type 2 diabetes, hard-on health was improved by 22%.

A trial of 86 people with eye damage from diabetes found that antioxidant therapy may improve eye health and reduce reactive oxygen species levels . Pycnogenol (125 mg/day) had the same effects in another study of 48 people with diabetes and high blood pressure. It also may help those on blood pressure medications to reduce their dose . Pycnogenol (200 mg/day) may reduce muscle cramps and pain according to a study of 66 healthy people, athletes, and those with venous problems after 4 weeks.

Citronella Oil: Repel Insects, Pain & Stress!

Some species of fungi and bacteria living in the air (Aspergillus flavus, A. fumigatus, A. niger and others) and their toxins cause difficulty in breathing, allergic rhinitis, watery eyes, headaches and flu-like symptoms. In 2004, when researchers from Vilnius Pedagogical University in Lithuania investigated the purifying biological activity of Pinus sylvestris L. Extract in order to find out its fungicidal benefits against airborne microorganisms, they found positive results.

This is simply because it is such a new method in the US and the West. A tincture is simply an alcohol–ethanol, drinking alcohol–extract of a plant . In this process, the plant is combined with alcohol and allowed to sit while the full extraction takes place.

It was noted that many couples reported improvements in libido and sexual function as a result of taking pine bark extract. For the Stanford study, the researchers recruited 130 overweight individuals who had blood pressure above an optimal level but were not taking medication for it. Stafford said the researchers felt these were the types of people who would be more likely to seek out dietary supplements as an alternative therapy.

Pine trees die naturally under the skirt but not towards the top. There’s a wreath of pine needles on the table in the room where I write now . The perfume of its oil is a harmoniser and a tonic in the house. I’ve had success using Marine Pine Bark from New Zealand for pain management in patients with chronic inflammatory conditions — a healthier option than the anti-inflammatory meds on offer. Maritime pine bark may interfere with immunosuppressant or immunostimulant herbs and supplements.

Demand For Sustainable And Natural Foaming Agents In Beverages Is Propelling The Pine Bark Extract Market:

The use of pine bark extract can reduce cardiovascular risk factors. One study finds that its use can dilate the small blood vessels in people with cardiovascular disease. It also protects against the smoking-caused platelet aggregation in smokers. It tends to have a mild anti-hypertensive effect too, thus helping with improved blood pressure. Another study used Japanese subjects to assess both erectile dysfunction and testosterone levels by giving them 60 mg per day of pine bark extract, combined with arginine and D-aspartic acid .

The OPCs in pine bark extract bind to the collagen in blood vessel walls making capillaries stronger and more elastic, which subsequently improves circulation and reduces blood pressure. Pine bark extract can be applied as healthy food and drug; functional ingredient of beverage and cosmetics ingredients. Both pine bark extract and arginine increase endogenous nitric oxide . The body requires NO to initiate and sustain penile erections through increasing vascular dilation. Berberine bark extract supplements are specifically beneficial for those with diabetes, metabolic syndrome, and risk for heart disease. It can also be used to successfully protect against chronic diseases and as a natural anti-aging supplement.

Angiotensin II concentrations in plasma were lowered in the placebo group to a larger extent than in the pine bark extract group. Heart rate, electrolytes and blood urea nitrogen were not changed during treatment in both groups of patients. Unwanted effects observed in both groups were of mild and transient nature, such as gastrointestinal problems, vertigo, headache and nausea. Our objective was to determine the effects of pine bark extract on blood pressure and other CVD risk factors in overweight and obese adults with higher-than-optimal systolic blood pressure. The study used a randomized, placebo-controlled, double-blind clinical trial design and achieved a sample size larger than most previous studies of pine bark extract. No significant effects on blood pressure, plasma lipoprotein cholesterol profile, glycemic metabolism, or inflammatory markers were observed between the pine bark extract group and the placebo group.

A 2002 study found for the first time that intake of this extract can improve hyperpigmentation in women having melisma. Another recent study has also pointed out that oral intake of the extract can drastically reduce pigmentation. Attention-deficit hyperactivity disorder, or ADHD, is a developmental condition that mostly affects children, although adults can suffer from it, too 13. It is characterized by inattentiveness, impulsive behavior and concentration problems. Although the exact cause of ADHD is unclear, environmental and genetic factors may contribute to its development. ADHD is commonly treated with prescription medicines and behavioral therapy.

There were no significant differences in blood pressure among any subgroups, while sporadic statistically significant differences, as might be expected by chance, were found for other outcomes. Although modifiable cardiovascular disease risk factors are common, some patients eschew conventional drug treatments in favor of natural alternatives. Can I consume CBD Gummies along with other CBD products?, a dietary supplement source of antioxidant oligomeric proanthocyanidin complexes, has multiple putative cardiovascular benefits. Studies published to date about the supplement have notable methodological limitations. What pine bark extract appears to do is reduce the oxidative stress that leads to the formation of circulatory and blood disorders in the first place. You can think of it kind of like the drains and piping in your house — when gunk builds up over time causing blockages.

Using Pycnogenol pine bark while pregnant or breastfeeding has not been clinically studied. While there is not evidence to suggest it’s dangerous, pregnancy safety remains unknown until adequate research takes place. Diabetic retinopathy, which can cause vision loss and blindness, was improved in 24 patients after they used the supplement for 3 months.

MASQUELIER’s® French Pine Bark Extract with Original OPCs is a dietary supplement and should be used to supplement the normal diet. Every organ, muscle and tissue in our body is fed and powered by nutrients from our blood. Our veins, arteries and capillaries ensure that these vital nutrients are delivered to where they are needed. Strengthens capillaries, improves circulation and delays aging of blood vessels. Read on to learn more about the product, such as the ingredients it contains, safety, and alternative options.

Historical reports indicate that pine needles were used by European explorers who reached the North American continent in the early 16th century . Learn how abnormally low or high levels can impact a man’s physical and mental health. Testosterone is crucial for many body processes, including fat loss and muscle growth. While some alternative low T treatments hold promise, they can also pose risks.

It is rich inproanthocyanidins, a special class of water-soluble antioxidant flavonoids, which are excellent free radical scavengers. There are several patented extracts of pine bark and it is difficult to determine which is the best one. The randomized, controlled study included 55 hypertensive patients with early signs of impaired kidney function. Both groups were treated with the anti-hypertensive medication Ramipril and one group of 29 patients took Pine tree extract in addition to the Ramipril.

Supplement Forms

It is a very strong and powerful antioxidant that supports the entire organism. It is made in the United States where the certification takes the place. The package contains 30 caps, and the price of this product is higher considering the quantity. Still, you can get the highest-quality product, and it is definitely worth the money, especially when you consider the advantages it provides.

The meta-analysis found that pycnogenol was effective in reducing blood platelet clumping. Furthermore, while aspirin significantly increased bleeding time due to decreased clumping, pycnogenol didn’t. The researchers found that one 200-milligram dose of pycnogenol was able to reduce smoking-induced blood platelet clumping for over 6 days. These findings suggest that pycnogenol may reduce blood clot-related heart disease risk, particularly in smokers. Pycnogenol is pine bark extract – just in a particular branded form.

This branded, patented French maritime pine bark extract is the most popular pine bark supplement. Pycnogenol is backed by hundreds of studies, including those showing skin benefits. In this study, 21 people were given Pycnogenol (1.1 mg/kg of body weight for 4 weeks, 1.66 mg for 4 more) to examine its protection against solar UV light. The supplementation increased the UV radiation levels needed to produce erythema , demonstrating that pine bark extract protects the skin against UV radiation. This effect may be explained by Pycnogenol reducing the activation of the NF-kappaB inflammatory pathway. Pine bark extract market is segmented on the basis of end use application which includes; health supplements, food additive and cosmetics.

This demand is expected to act as a driving force for the pine bark extract market. Pine bark extract has several health benefits, for instance, it helps cure allergies & asthma as well as improves athletic performances, circulation problems, mental function and eye diseases. A wide variety of pine species are distributed across the globe, and key regions associated with the pine bark extract market include North America, Latin America, APEJ and Western Europe. The producers of pine bark extract are keen on enhancing their production capacities to fulfil the demands of consumers as well as to expand their market share globally over the forecast period. In the coming years, the pine bark extract market is expected to increase significantly owing to all the health benefits obtained from pine bark extract.